A potentially HUGE finding in a preprint suggests a radically different mechanism for hydroxychloroquine’s action in COVID19. TL;DR in layman language: that a lot of the hypoxyia (oxygen starvation) of severe COVID-19 patients is due to hemoglobin in red blood cells being disrupted by the virus (as it is by the malaria pathogen), and that hydroxychloroquine protects hemoglobin in both diseases. A layman’s discussion can be found here.
“Masgramondou” has an origin hypothesis for the outbreak that sounds disturbingly plausible to anyone who subscribes to the “incompetence before malice” or “c*ck-up before conspiracy” principle.
How helpful is soap against COVID-19? If yes, why? The American Chemical Society has a helpful YouTube video https://www.youtube.com/watch?v=K2pMVimI2bw
The leader article of German center-right daily Die Welt is entitled: “the end of globalization as we know it” https://www.welt.de/wirtschaft/article207072567/Corona-Krise-Unternehmen-aendern-ihre-Lieferketten.html
Ventilator outcomes discussed by Roger Seheult MD https://www.youtube.com/watch?v=uaIzj3s3p4A&t=7s . In another video, he weighs in on the beneficial effect of sauna baths for immunity in general and in COVID-19 in particular https://www.youtube.com/watch?v=EFRwnhfWXxo (hat tip: Mrs. Arbel) Finnish statistics so far look enviable.
My friend Tom Knighton lives in Dougherty County in rural GA, which found itself coping with a fierce COVID-19 outbreak following a “super-spreader” event at a funeral. But it seems they are now seeing the proverbial light at the end of the tunnel. https://www.walb.com/2020/04/05/phoebe-releases-sundays-covid-numbers/
Israel, which saw super-spreader events during Purim parties a month ago, is now taking the drastic step of imposing a curfew from a few hours before the Passover seder until the next morning. Seders are to be done strictly in the home, nuclear family only, no guests.
Japanhttps://www.worldometers.info/coronavirus/country/japan, which was very reluctant to do so, finally declares pandemic emergency
And Instapundit minces no words in USA Today .
UPDATE: via David Bernstein, interactive COVID-19 map of the New York City metropolitan area. Counterintuitively, Manhattan is not the worst hit pro capita: that extremely dubious honor falls to the nearer commuter counties.
NY Gov. Andrew Cuomo, hovewer, points to an apparent “flattening of the curve” in hard-hit NYC.